delayed embryo transfer

Delayed Embryo Transfer

During the menstrual cycle, estrogen levels naturally peak just before ovulation. This rise in estrogen triggers ovulation, causing the ovaries to begin producing progesterone. Progesterone then triggers development of the endometrial lining in the uterus. For pregnancy to develop, a fertilized egg needs to implant in the endometrial lining and begin to grow. Because the body produces progesterone in response to ovulation, in ideal conditions the endometrial lining develops at the right rate to nurture the fertilized egg. That synchronization creates the best environment for implantation.
Delayed Embryo Transfer

Desynchronization in IVF

During IVF treatment, the ovaries are stimulated, and estrogen levels peak at much higher levels than in natural cycles. This artificially-induced peak in estrogen triggers progesterone production.

However, if progesterone levels increase too early, the endometrial lining develops too quickly to support the embryos. This desynchronization between the embryos and the endometrial lining reduces the likelihood of a successful implantation.

For this reason, IVF patients take medications to suppress progesterone production, but in some patients these medications are not effective.

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Desynchronization in IVF

How Delayed Embryo Transfer Works

Delayed Embryo Transfer helps avoid desynchronization. Instead of implanting eggs while the body’s cycle is altered by IVF, embryos are first retrieved and frozen.

Freezing techniques have advanced significantly in recent years. Older freezing techniques yielded few vital embryos, but the advanced techniques used at Aspire substantially reduce loss rates.

Once the body has had a chance to recover from the stress of IVF, and has returned to a more normal cycle, the eggs are then thawed and implanted. These advanced techniques resemble natural conception and result in increased pregnancy and live birth rates, decreased miscarriages, and healthier babies.

Benefits of Delayed Embryo Transfer

Recent studies have shown that IVF using a Delayed Embryo Transfer greatly increases the chance for successful implantation. For this reason, the procedure is part of our standard of care, and is an integral part of our IVF treatments, at no additional cost to patients.